Ryan S GrayAssistant Professor of Pediatrics
Main Office:DPR 2.284
Phone:+1 512 495 5052
Single nucleotide genetics changes can act alone or in concert to affect the development or homeostasis of tissues and organ systems. The Gray lab takes an integrated approach to understanding this process combining Human genomic data with experimental modeling in zebrafish and mouse model organisms.
Currently, they focus on understanding defects of the vertebral column/ spine commonly called Adolescent Idiopathic Scoliosis (AIS). They utilize forward and reverse genetic approaches to identify and model AIS and employ a wide-range of molecular, biochemical, and biomedical imaging techniques to understand the pathophysiology of these genetic models of scoliosis. By considering all of these components and how they affect the spine, the Gray group hopes to build a comprehensive picture of spine development and homeostasis.