Han K, Lou DI, Sawyer SL (2011) Identification of a genomic reservoir for new TRIM genes in primate genomes. PLoS Genetics, 7(12): e1002388.
McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM (2010) Systematic discovery of nonobvious human disease models through orthologous phenotypes.Proc Natl Acad Sci U S A, 107(14):6544-9.
Hughes RA, Miklos AE, Ellington AD (2011) Gene synthesis: methods and applications. Methods Enzymol 498:277-309.
Hughes RA, Ellington AD (2010) Rational design of an orthogonal tryptophanyl nonsense suppressor tRNA. Nucleic Acids Res 38(19):6813-30.
Tabor JJ, Salis HM, Simpson ZB, Chevalier AA, Levskaya A, Marcotte EM, Voigt CA, Ellington AD (2009) A synthetic genetic edge detection program. Cell 137:1272-81.
Levy M, Ellington AD (2008) Directed Evolution of Streptavidin Variants Using IVC. Chem Biol 15:979-89.
Li B, Ellington AD, Chen X (2011) Rational, modular adaptation of enzyme-free DNA circuits to multiple detection methods. Nucleic Acids Res 39(16):e110.
The Marcotte lab is developing novel systems-biology approaches to mine the evolutionary relationships between genes. These methods have been used to predict surprising relationships between genes and human disease, including: Finding disease genes from lower organisms. New algorithms (the phenolog …