Publications

Significant Publications

Cha HJ, Byrom M, Mead PE, Ellington ADWallingford JBMarcotte EM (2012).  Evolutionarily Repurposed Networks Reveal the Well-Known Antifungal Drug Thiabendazole to Be a Novel Vascular Disrupting Agent.  PLoS Biology.  10(8):e1001379  |  Pubmed

Tabor JJ, Salis H, Simpson ZB, Chevalier AA, Levskaya A, Marcotte EM, Voigt CA, Ellington AD (2009).  A Synthetic Genetic Edge Detection Program.  Cell.  137:1272-1281  |  Pubmed

Gray RS, Abitua PB, Wlodarczyk BJ, Blanchard O, Lee I, Weiss G, Marcotte EMWallingford JB, Finnel RH (2009).  The planar cell polarity effector protein Fuzzy is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development.  Nature Cell Biology.  11:1225-1232  |  Pubmed

Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM (2008).  A single network comprising the majority of genes accurately predicts the phenotypic effects of gene perturbation in Caenorhabditis elegans.  Nature Genetics.  40:181-188  |  Pubmed

Lu P, Vogel C, Wang R, Yao X, Marcotte EM (2007).  Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation.  Nature Biotechnol.  25:117-120  |  Pubmed

Vogel C, Marcotte EM (2012) Insights into the regulation of protein abundance from proteomic and transcriptomic analyses.Nat Rev Genet, 13:227-32 (2012)

Lee I, Seo Y-S, Coltrane D, Hwang S, Oha T, Marcotte EM, Ronald PC (2011) Genetic dissection of the biotic stress response using a genome-scale gene network for rice. Proc Natl Acad Sci USA, 108(45):18548-53.

Han K, Lou DI, Sawyer SL (2011) Identification of a genomic reservoir for new TRIM genes in primate genomes. PLoS Genetics, 7(12): e1002388.

McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM (2010) Systematic discovery of nonobvious human disease models through orthologous phenotypes.Proc Natl Acad Sci U S A, 107(14):6544-9.

Hughes RA, Miklos AE, Ellington AD (2011) Gene synthesis: methods and applications. Methods Enzymol 498:277-309.

Recent Publications

Cha HJ, Byrom M, Mead PE, Ellington ADWallingford JBMarcotte EM (2012).  Evolutionarily Repurposed Networks Reveal the Well-Known Antifungal Drug Thiabendazole to Be a Novel Vascular Disrupting Agent.  PLoS Biology.  10(8):e1001379  |  Pubmed

Tabor JJ, Salis H, Simpson ZB, Chevalier AA, Levskaya A, Marcotte EM, Voigt CA, Ellington AD (2009).  A Synthetic Genetic Edge Detection Program.  Cell.  137:1272-1281  |  Pubmed

Gray RS, Abitua PB, Wlodarczyk BJ, Blanchard O, Lee I, Weiss G, Marcotte EMWallingford JB, Finnel RH (2009).  The planar cell polarity effector protein Fuzzy is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development.  Nature Cell Biology.  11:1225-1232  |  Pubmed

Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM (2008).  A single network comprising the majority of genes accurately predicts the phenotypic effects of gene perturbation in Caenorhabditis elegans.  Nature Genetics.  40:181-188  |  Pubmed

Lu P, Vogel C, Wang R, Yao X, Marcotte EM (2007).  Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation.  Nature Biotechnol.  25:117-120  |  Pubmed

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